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Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome

The neurodevelopmental disorder Angelman syndrome (AS) is characterized by intellectual disability, motor dysfunction, distinct behavioral aspects, and epilepsy. AS is caused by a loss of the maternally expressed UBE3A gene, and many of the symptoms are recapitulated in a Ube3a mouse model of this s...

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Bibliografiske detaljer
Udgivet i:Front Cell Neurosci
Main Authors: Wang, Tiantian, van Woerden, Geeske M., Elgersma, Ype, Borst, J. Gerard G.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758499/
https://ncbi.nlm.nih.gov/pubmed/29354033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00418
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