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Endostar combined with chemotherapy in a pediatric osteosarcoma with pulmonary metastasis and malignant pleural effusion: A case report

RATIONALE: Angiogenesis is a key factor for tumor growth and metastasis both in cancer and sarcoma. Endostar, a novel safe and well-tolerated recombinant human endostatin, can suppress the expression of VEGF and the activation of ERK, MAPK, and AKT, and then inhibit tumor progression. PATIENT CONCER...

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Publicado en:Medicine (Baltimore)
Main Authors: Jiang, Sujing, Wang, Guannan, Dong, Ying
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Health 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758138/
https://ncbi.nlm.nih.gov/pubmed/29390436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000009077
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