Combined (1)H-Detected Solid-State NMR Spectroscopy and Electron Cryotomography to Study Membrane Proteins across Resolutions in Native Environments

Membrane proteins remain challenging targets for structural biology, despite much effort, as their native environment is heterogeneous and complex. Most methods rely on detergents to extract membrane proteins from their native environment, but this removal can significantly alter the structure and f...

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Publicat a:Structure
Autors principals: Baker, Lindsay A., Sinnige, Tessa, Schellenberger, Pascale, de Keyzer, Jeanine, Siebert, C. Alistair, Driessen, Arnold J.M., Baldus, Marc, Grünewald, Kay
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758107/
https://ncbi.nlm.nih.gov/pubmed/29249608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.11.011
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