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Analysis of CYP2C19 Genetic Polymorphism in a Large Ethnic Hakka Population in Southern China

BACKGROUND: Cytochrome P450 (CYP) 2C19 is an enzyme involved in the bioactivation of various important therapeutic drugs, from pro-drugs to an active inhibitor of platelet action. Variants in the CYP2C19 gene influence the pharmacokinetics and clinical response to antiplatelet drugs such as clopidog...

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Dettagli Bibliografici
Pubblicato in:Med Sci Monit
Autori principali: Zhong, Zhixiong, Hou, Jingyuan, Li, Bing, Zhang, Qifeng, Liu, Sudong, Li, Cunren, Liu, Zhidong, Yang, Min, Zhong, Wei, Zhao, Pingsen
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757864/
https://ncbi.nlm.nih.gov/pubmed/29288619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.905337
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