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RACKI induces chemotherapy resistance in esophageal carcinoma by upregulating the PI3K/AKT pathway and Bcl-2 expression

INTRODUCTION: Accumulating evidence indicates that RACK1 is involved in the progression of tumors. We aimed to evaluate the function of RACK1 in esophageal squamous cell carcinoma (ESCC) and its role in the mechanism of chemotherapy resistance. MATERIALS AND METHODS: Transfected ESCC cell lines with...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Liu, Bowen, Wang, Cong, Chen, Pengxiang, Cheng, Bo, Cheng, Yufeng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757499/
https://ncbi.nlm.nih.gov/pubmed/29379302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S152818
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