Reasons for discontinuing clozapine: A cohort study of patients commencing treatment

BACKGROUND: Clozapine is uniquely effective in the management of treatment-resistant schizophrenia (TRS). However, a substantial proportion of patients discontinue treatment and this carries a poor prognosis. METHODS: We investigated the risk factors, reasons and timing of clozapine discontinuation...

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Udgivet i:Schizophr Res
Main Authors: Legge, Sophie E., Hamshere, Marian, Hayes, Richard D., Downs, Johnny, O'Donovan, Michael C., Owen, Michael J., Walters, James T.R., MacCabe, James H.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science Publisher B. V 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756540/
https://ncbi.nlm.nih.gov/pubmed/27211516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2016.05.002
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