Activation of a chondrocyte volume-sensitive Cl(−) conductance prior to macroscopic cartilage lesion formation in the rabbit knee anterior cruciate ligament transection osteoarthritis model

OBJECTIVE: The anterior cruciate ligament transection (ACLT) rabbit osteoarthritis (OA) model confers permanent knee instability and induces joint degeneration. The degeneration process is complex, but includes chondrocyte apoptosis and OA-like loss of cartilage integrity. Previously, we reported th...

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Publicado no:Osteoarthritis Cartilage
Main Authors: Kumagai, K., Toyoda, F., Staunton, C.A., Maeda, T., Okumura, N., Matsuura, H., Matsusue, Y., Imai, S., Barrett-Jolley, R.
Formato: Artigo
Idioma:Inglês
Publicado em: W.B. Saunders For The Osteoarthritis Research Society 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756537/
https://ncbi.nlm.nih.gov/pubmed/27266646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2016.05.019
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