Deletion of Protein Kinase D1 in Osteoprogenitor Cells Results in Decreased Osteogenesis in vitro and Reduced Bone Mineral Density in vivo

Protein kinase D1 (PRKD1) is thought to play a role in a number of cellular functions, including proliferation and differentiation. We hypothesized that PRKD1 in bone marrow-derived mesenchymal stem cells (BMMSC) could modulate osteogenesis. In BMMSCs from floxed PRKD1 mice, PRKD1 ablation with aden...

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發表在:Mol Cell Endocrinol
Main Authors: Bollag, Wendy B., Choudhary, Vivek, Zhong, Qing, Ding, Ke-Hong, Xu, Jianrui, Elsayed, Ranya, Yu, Kanglun, Su, Yun, Bailey, Lakiea J., Shi, Xing-Ming, Elsalanty, Mohammed, Johnson, Maribeth H., McGee-Lawrence, Meghan E., Isales, Carlos M.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756499/
https://ncbi.nlm.nih.gov/pubmed/28811183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2017.08.005
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