Role and regulation of Abelson tyrosine kinase in Crk-associated substrate/profilin-1 interaction and airway smooth muscle contraction

BACKGROUND: Airway smooth muscle contraction is critical for maintenance of appropriate airway tone, and has been implicated in asthma pathogenesis. Smooth muscle contraction requires an “engine” (myosin activation) and a “transmission system” (actin cytoskeletal remodeling). However, the mechanisms...

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Veröffentlicht in:Respir Res
Hauptverfasser: Wang, Yinna, Rezey, Alyssa C., Wang, Ruping, Tang, Dale D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756382/
https://ncbi.nlm.nih.gov/pubmed/29304860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0709-4
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