An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression

BACKGROUND: We conducted an epigenome-wide association study (EWAS) on obesity in healthy youth and young adults and further examined to what extent identified signals influenced gene expression and were independent of cell type composition and obesity-related cardio-metabolic risk factors. Genome-w...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Wang, Xiaoling, Pan, Yue, Zhu, Haidong, Hao, Guang, Huang, Yisong, Barnes, Vernon, Shi, Huidong, Snieder, Harold, Pankow, James, North, Kari, Grove, Megan, Guan, Weihua, Demerath, Ellen, Dong, Yanbin, Su, Shaoyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756368/
https://ncbi.nlm.nih.gov/pubmed/29312471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0435-2
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