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Development of a copper-clioquinol formulation suitable for intravenous use

Clioquinol (CQ) is an FDA-approved topical antifungal agent known to kill cancer cells. This facilitated the initiation of clinical trials in patients with refractory hematologic malignancies. These repurposing efforts were not successful; this was likely due to low intracellular levels of the drug...

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Bibliografski detalji
Izdano u:Drug Deliv Transl Res
Glavni autori: Wehbe, Moe, Malhotra, Armaan K., Anantha, Malathi, Lo, Cody, Dragowska, Wieslawa H., Dos Santos, Nancy, Bally, Marcel B.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756275/
https://ncbi.nlm.nih.gov/pubmed/29247315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0455-7
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