Development of a copper-clioquinol formulation suitable for intravenous use

Clioquinol (CQ) is an FDA-approved topical antifungal agent known to kill cancer cells. This facilitated the initiation of clinical trials in patients with refractory hematologic malignancies. These repurposing efforts were not successful; this was likely due to low intracellular levels of the drug...

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Publicat a:Drug Deliv Transl Res
Autors principals: Wehbe, Moe, Malhotra, Armaan K., Anantha, Malathi, Lo, Cody, Dragowska, Wieslawa H., Dos Santos, Nancy, Bally, Marcel B.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756275/
https://ncbi.nlm.nih.gov/pubmed/29247315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0455-7
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