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Development of a copper-clioquinol formulation suitable for intravenous use
Clioquinol (CQ) is an FDA-approved topical antifungal agent known to kill cancer cells. This facilitated the initiation of clinical trials in patients with refractory hematologic malignancies. These repurposing efforts were not successful; this was likely due to low intracellular levels of the drug...
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| Publicat a: | Drug Deliv Transl Res |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer US
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5756275/ https://ncbi.nlm.nih.gov/pubmed/29247315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0455-7 |
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