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Theoretical perspectives on central chemosensitivity: CO(2)/H(+)-sensitive neurons in the locus coeruleus
Central chemoreceptors are highly sensitive neurons that respond to changes in pH and CO(2) levels. An increase in CO(2)/H(+) typically reflects a rise in the firing rate of these neurons, which stimulates an increase in ventilation. Here, we present an ionic current model that reproduces the basic...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5755939/ https://ncbi.nlm.nih.gov/pubmed/29267284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005853 |
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