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A DOUBLE BLIND, PLACEBO-CONTROLLED STUDY OF RITUXIMAB IN PATIENTS WITH STIFF PERSON SYNDROME

OBJECTIVE: In Stiff-Person Syndrome (SPS), an antibody-mediated impaired GABAergic neurotransmission is believed to cause muscle stiffness and spasms. Patients improve with GABA-enhancing drugs and IVIg, but several respond poorly and remain disabled. The need for more effective therapy prompted a t...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Dalakas, Marinos C., Rakocevic, Goran, Dambrosia, James M., Alexopoulos, Harry, McElroy, Beverly
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755707/
https://ncbi.nlm.nih.gov/pubmed/28749549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25002
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