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A DOUBLE BLIND, PLACEBO-CONTROLLED STUDY OF RITUXIMAB IN PATIENTS WITH STIFF PERSON SYNDROME
OBJECTIVE: In Stiff-Person Syndrome (SPS), an antibody-mediated impaired GABAergic neurotransmission is believed to cause muscle stiffness and spasms. Patients improve with GABA-enhancing drugs and IVIg, but several respond poorly and remain disabled. The need for more effective therapy prompted a t...
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Publicado no: | Ann Neurol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5755707/ https://ncbi.nlm.nih.gov/pubmed/28749549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25002 |
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