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Method for Labeling Transcripts in Individual Escherichia coli Cells for Single-molecule Fluorescence In Situ Hybridization Experiments

A method is described for labeling individual messenger RNA (mRNA) transcripts in fixed bacteria for use in single-molecule fluorescence in situ hybridization (smFISH) experiments in E. coli. smFISH allows the measurement of cell-to-cell variability in mRNA copy number of genes of interest, as well...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Arbel-Goren, Rinat, Shapira, Yonatan, Stavans, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755673/
https://ncbi.nlm.nih.gov/pubmed/29286479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56600
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