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Using Fluorescence In Situ Hybridization (FISH) to Monitor the State of Arm Cohesion in Prometaphase and Metaphase I Drosophila Oocytes

In humans, chromosome segregation errors in oocytes are responsible for the majority of miscarriages and birth defects. Moreover, as women age, their risk of conceiving an aneuploid fetus increases dramatically and this phenomenon is known as the maternal age effect. One requirement for accurate chr...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Perkins, Adrienne T., Bickel, Sharon E.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755544/
https://ncbi.nlm.nih.gov/pubmed/29286418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56802
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