RNA virus interference via CRISPR/Cas13a system in plants

BACKGROUND: CRISPR/Cas systems confer immunity against invading nucleic acids and phages in bacteria and archaea. CRISPR/Cas13a (known previously as C2c2) is a class 2 type VI-A ribonuclease capable of targeting and cleaving single-stranded RNA (ssRNA) molecules of the phage genome. Here, we employ...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Aman, Rashid, Ali, Zahir, Butt, Haroon, Mahas, Ahmed, Aljedaani, Fatimah, Khan, Muhammad Zuhaib, Ding, Shouwei, Mahfouz, Magdy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755456/
https://ncbi.nlm.nih.gov/pubmed/29301551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1381-1
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