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Preclinical and clinical implications of TERT promoter mutation in glioblastoma multiforme
The promoter region of the telomerase reverse transcriptase gene (TERT) is mutated in a subpopulation of patients with glioblastoma multiforme (GBM). In the present study, preclinical and clinical implications of the mutation were analyzed in 25 GBMs to evaluate its utility as a therapeutic target....
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Publicado no: | Oncol Lett |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
D.A. Spandidos
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5755188/ https://ncbi.nlm.nih.gov/pubmed/29344264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7196 |
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