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Preclinical and clinical implications of TERT promoter mutation in glioblastoma multiforme

The promoter region of the telomerase reverse transcriptase gene (TERT) is mutated in a subpopulation of patients with glioblastoma multiforme (GBM). In the present study, preclinical and clinical implications of the mutation were analyzed in 25 GBMs to evaluate its utility as a therapeutic target....

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Jeong, Da Eun, Woo, Seon Rang, Nam, Hyun, Nam, Do-Hyun, Lee, Jae-Ho, Joo, Kyeung Min
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755188/
https://ncbi.nlm.nih.gov/pubmed/29344264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7196
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