Electrostatic confinement and manipulation of DNA molecules for genome analysis

Very large DNA molecules enable comprehensive analysis of complex genomes, such as human, cancer, and plants because they span across sequence repeats and complex somatic events. When physically manipulated, or analyzed as single molecules, long polyelectrolytes are problematic because of mechanical...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kounovsky-Shafer, Kristy L., Hernandez-Ortiz, Juan P., Potamousis, Konstantinos, Tsvid, Gene, Place, Michael, Ravindran, Prabu, Jo, Kyubong, Zhou, Shiguo, Odijk, Theo, de Pablo, Juan J., Schwartz, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754773/
https://ncbi.nlm.nih.gov/pubmed/29203667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711069114
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