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Incretin concept revised: The origin of the insulinotropic function of glucagon‐like peptide‐1 – the gut, the islets or both?

Incretins comprise a pair of gut hormones, glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1), which are secreted in response to food ingestion and enhance glucose‐dependent insulin secretion from pancreatic β‐cells. Immediately after secretion, GLP‐1 is degraded...

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Podrobná bibliografie
Vydáno v:J Diabetes Investig
Hlavní autoři: Yabe, Daisuke, Seino, Yusuke, Seino, Yutaka
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754537/
https://ncbi.nlm.nih.gov/pubmed/28746743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12718
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