KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation

The three-dimensional structure of chromatin organized by genomic loops facilitates RNA polymerase II access to distal promoters. The Kaposi’s sarcoma-associated herpesvirus (KSHV) lytic transcriptional program is initiated by a single viral transactivator, K-Rta. Here we report the KSHV genomic str...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Campbell, Mel, Watanabe, Tadashi, Nakano, Kazushi, Davis, Ryan R., Lyu, Yuanzhi, Tepper, Clifford G., Durbin-Johnson, Blythe, Fujimuro, Masahiro, Izumiya, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754359/
https://ncbi.nlm.nih.gov/pubmed/29302027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02089-9
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