Concurrent ROS1 gene rearrangement and KRAS mutation in lung adenocarcinoma: A case report and literature review

Lung adenocarcinomas with gene rearrangement in the receptor tyrosine kinase ROS1 have emerged as a rare molecular subtype. Although these lung adenocarcinomas respond to ROS1tyrosine kinase inhibitors, many patients ultimately acquire resistance. ROS1gene rearrangement is generally mutually exclusi...

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Vydáno v:Thorac Cancer
Hlavní autoři: Zhu, You‐cai, Lin, Xue‐ping, Li, Xiao‐feng, Wu, Li‐xin, Chen, Hua‐fei, Wang, Wen‐xian, Xu, Chun‐wei, Shen, Jian‐fa, Wei, Jian‐guo, Du, Kai‐qi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons Australia, Ltd 2017
Témata:
Case Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754306/
https://ncbi.nlm.nih.gov/pubmed/28971587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.12518
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