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PKC-dependent phosphorylation of Munc18a at Ser313 in activated RBL-2H3 cells

Protein Kinase C (PKC) regulates the release of pro-inflammatory compounds from IgE/antigen-activated mast cells by unknown mechanisms. In this study, we show for the first time that PKC inhibitor Ro-03-0432, which inhibits RBL-2H3 exocytosis/degranulation in a concentration dependent fashion, preve...

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Détails bibliographiques
Publié dans:Inflamm Res
Auteurs principaux: Adhikari, Pratikshya, Xu, Hao
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754224/
https://ncbi.nlm.nih.gov/pubmed/28983637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-017-1097-4
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