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Global accumulation of circRNAs during aging in Caenorhabditis elegans

BACKGROUND: Circular RNAs (CircRNAs) are a newly appreciated class of RNAs that lack free 5′ and 3′ ends, are expressed by the thousands in diverse forms of life, and are mostly of enigmatic function. Ostensibly due to their resistance to exonucleases, circRNAs are known to be exceptionally stable....

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Cortés-López, Mariela, Gruner, Matthew R., Cooper, Daphne A., Gruner, Hannah N., Voda, Alexandru-Ioan, van der Linden, Alexander M., Miura, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753478/
https://ncbi.nlm.nih.gov/pubmed/29298683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4386-y
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