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Randomized, Controlled Trial of TRC101 to Increase Serum Bicarbonate in Patients with CKD

BACKGROUND AND OBJECTIVES: Metabolic acidosis is common in patients with CKD and has significant adverse effects on kidney, muscle, and bone. We tested the efficacy and safety of TRC101, a novel, sodium-free, nonabsorbed hydrochloric acid binder, to increase serum bicarbonate in patients with CKD an...

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Detalhes bibliográficos
Publicado no:Clin J Am Soc Nephrol
Main Authors: Bushinsky, David A., Hostetter, Thomas, Klaerner, Gerrit, Stasiv, Yuri, Lockey, Claire, McNulty, Sarah, Lee, Angela, Parsell, Dawn, Mathur, Vandana, Li, Elizabeth, Buysse, Jerry, Alpern, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753317/
https://ncbi.nlm.nih.gov/pubmed/29102959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.07300717
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