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A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 Influenza A Virus in Cells

Vaccination is the primary strategy for influenza prevention and control. However, egg-based vaccines, the predominant production platform, have several disadvantages, including the emergence of viral antigenic variants that can be induced during egg passage. These limitations have prompted the deve...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Wen, Feng, Li, Lei, Zhao, Nan, Chiang, Meng-Jung, Xie, Hang, Cooley, Jim, Webby, Richard, Wang, Peng George, Wan, Xiu-Feng
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752953/
https://ncbi.nlm.nih.gov/pubmed/29118117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01621-17
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