Notch signaling negatively regulates BMP9-induced osteogenic differentiation of mesenchymal progenitor cells by inhibiting JunB expression

Although interaction between BMP and Notch signaling has been demonstrated to be crucial for osteogenic differentiation of mesenchymal stem cells (MSCs), the precise molecular mechanism remains unknown. Here, we show that Notch intracellular domain (NICD) overexpression inhibits BMP9-induced C3H10T1...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wang, Nan, Liu, Wei, Tan, Tao, Dong, Chao-Qun, Lin, Duan-Yang, Zhao, Jun, Yu, Chang, Luo, Xiao-Ji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752550/
https://ncbi.nlm.nih.gov/pubmed/29312637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22763
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