Intratumoral heterogeneity and TERT promoter mutations in progressive/higher-grade meningiomas

BACKGROUND: Recent studies have reported mutations in the telomerase reverse transcriptase promoter (TERTp) in meningiomas. We sought to determine the frequency, clonality and clinical significance of telomere gene alterations in a cohort of patients with progressive/higher-grade meningiomas. METHOD...

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Udgivet i:Oncotarget
Main Authors: Juratli, Tareq A., Thiede, Christian, Koerner, Mara V.A., Tummala, Shilpa S., Daubner, Dirk, Shankar, Ganesh M., Williams, Erik A., Martinez-Lage, Maria, Soucek, Silke, Robel, Katja, Penson, Tristan, Krause, Mechthild, Appold, Steffen, Meinhardt, Matthias, Pinzer, Thomas, Miller, Julie J., Krex, Dietmar, Ely, Heather A., Silverman, Ian M., Christiansen, Jason, Schackert, Gabriele, Wakimoto, Hiroaki, Kirsch, Matthias, Brastianos, Priscilla K., Cahill, Daniel P.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752516/
https://ncbi.nlm.nih.gov/pubmed/29312603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22650
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