Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4-MAPK-NF-κB/AP-1 signaling

We investigated the mechanisms that induce atrophy of the chicken bursa of Fabricius (BF) upon lipopolysaccharide (LPS) treatment in young chicks. LPS treatment resulted in ∼36% decrease in bursal weight within 36 h (P < 0.01). Histological analysis showed infiltration of eosinophilic heterophils...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ansari, Abdur Rahman, Li, Ning-Ya, Sun, Zhi-Jian, Huang, Hai-Bo, Zhao, Xing, Cui, Lei, Hu, Ya-Fang, Zhong, Ju-Ming, Karrow, Niel A., Liu, Hua-Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752450/
https://ncbi.nlm.nih.gov/pubmed/29312537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19964
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