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The Developing Role of Anti–Epidermal Growth Factor Receptor Agents in the Treatment of Advanced or Metastatic Colorectal Cancer

The first studies of epidermal growth factor receptor (EGFR) inhibitors in metastatic colorectal cancer were begun before the predictive role of RAS mutations had been elucidated. Secondary analyses of many large randomized trials have shown that mutations in exons 2–4 of KRAS and NRAS, BRAF V600E m...

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Detalhes bibliográficos
Publicado no:Oncology (Williston Park)
Main Authors: Ursem, Carling, Venook, Alan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752316/
https://ncbi.nlm.nih.gov/pubmed/29179247
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