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Therapeutic drug repositioning using personalized proteomics of liquid biopsies

BACKGROUND. In patients with limited response to conventional therapeutics, repositioning of already approved drugs can bring new, more effective options. Current drug repositioning methods, however, frequently rely on retrospective computational analyses and genetic testing — time consuming methods...

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Velez, Gabriel, Bassuk, Alexander G., Colgan, Diana, Tsang, Stephen H., Mahajan, Vinit B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752263/
https://ncbi.nlm.nih.gov/pubmed/29263305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97818
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