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Therapeutic drug repositioning using personalized proteomics of liquid biopsies

BACKGROUND. In patients with limited response to conventional therapeutics, repositioning of already approved drugs can bring new, more effective options. Current drug repositioning methods, however, frequently rely on retrospective computational analyses and genetic testing — time consuming methods...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Velez, Gabriel, Bassuk, Alexander G., Colgan, Diana, Tsang, Stephen H., Mahajan, Vinit B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752263/
https://ncbi.nlm.nih.gov/pubmed/29263305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97818
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