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Epigallocatechin-3-gallate inhibits inflammation and epithelial-mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma

Asthma is a chronic disease associated with hyper-responsiveness, obstruction and remodeling of the airways. Epithelial-mesenchymal transition (EMT) has an important role in these alterations and may account for the accumulation of subepithelial mesenchymal cells, thus contributing to airway hyperre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Med
Hauptverfasser: Yang, Nan, Zhang, Han, Cai, Xuxu, Shang, Yunxiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752157/
https://ncbi.nlm.nih.gov/pubmed/29207033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3292
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