Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype

Regulatory factor X4 (RFX4) isoform 1 is a recently discovered isoform of the winged helix transcription factor RFX4, which can bind to X-box consensus sequences that are enriched in the promoters of cilia-related genes. Early insertional mutagenesis studies in mice first identified this isoform, an...

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Veröffentlicht in:PLoS One
Hauptverfasser: Xu, Ping, Morrison, James P., Foley, Julie F., Stumpo, Deborah J., Ward, Toni, Zeldin, Darryl C., Blackshear, Perry J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752003/
https://ncbi.nlm.nih.gov/pubmed/29298325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190561
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