Inhibition of TDP43-Mediated SNHG12-miR-195-SOX5 Feedback Loop Impeded Malignant Biological Behaviors of Glioma Cells

Long non-coding RNA (lncRNA) dysregulation is involved in tumorigenesis and regulation of diverse cellular processes in gliomas. lncRNA SNHG12 is upregulated and promotes cell growth in human osteosarcoma cells. TAR-DNA binding protein 43 (TDP43) functions as an oncogene in various tumors by modulat...

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Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Liu, Xiaobai, Zheng, Jian, Xue, Yixue, Qu, Chengbin, Chen, Jiajia, Wang, Zhenhua, Li, Zhen, Zhang, Lei, Liu, Yunhui
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751968/
https://ncbi.nlm.nih.gov/pubmed/29499929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.12.001
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