Neither non-toxigenic Staphylococcus aureus nor commensal S. epidermidi activates NLRP3 inflammasomes in human conjunctival goblet cells

PURPOSE: The conjunctiva is a wet mucosal surface surrounding the cornea that is continuously exposed to pathogens. Nevertheless, persistent inflammation is not observed. We examined if the NOD-like receptor pyrin domain 3 (NLRP3) inflammasome functions as a sensor that distinguishes commensal and n...

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Veröffentlicht in:BMJ Open Ophthalmol
Hauptverfasser: Li, Dayu, Hodges, Robin R, Bispo, Paulo, Gilmore, Michael S, Gregory-Ksander, Meredith, Dartt, Darlene A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751869/
https://ncbi.nlm.nih.gov/pubmed/29354725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjophth-2017-000101
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