Hemopexin promotes angiogenesis via up-regulating HO-1 in rats after cerebral ischemia-reperfusion injury

BACKGROUND: Ischemia-reperfusion (I/R) is a critical pathophysiological change of ischemic stroke. Heme-oxygenase-1 (HO-1) is a rate-limiting enzyme of eliminating excessive free heme by combining with hemopexin (HPX), a plasma protein contributing to alleviating infarct size due to ischemia stroke....

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Bibliografiske detaljer
Udgivet i:BMC Anesthesiol
Main Authors: Dong, Beibei, Zhang, Zhishen, Xie, Keliang, Yang, Yongyan, Shi, Yuan, Wang, Chenxu, Yu, Yonghao
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751849/
https://ncbi.nlm.nih.gov/pubmed/29298658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-017-0466-4
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