Population-Specific Associations of Deleterious Rare Variants in Coding Region of P2RY1–P2RY12 Purinergic Receptor Genes in Large-Vessel Ischemic Stroke Patients

The contribution of low-frequency and damaging genetic variants associated with platelet function to ischemic stroke (IS) susceptibility remains unknown. We employed a deep re-sequencing approach in Polish patients in order to investigate the contribution of rare variants (minor allele frequency, MA...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Janicki, Piotr K., Eyileten, Ceren, Ruiz-Velasco, Victor, Sedeek, Khaled Anwar, Pordzik, Justyna, Czlonkowska, Anna, Kurkowska-Jastrzebska, Iwona, Sugino, Shigekazu, Imamura-Kawasawa, Yuka, Mirowska-Guzel, Dagmara, Postula, Marek
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751280/
https://ncbi.nlm.nih.gov/pubmed/29232918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122678
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