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Systematic Analysis of Transcriptomic Profile of Renal Cell Carcinoma under Long-Term Hypoxia Using Next-Generation Sequencing and Bioinformatics

Patients with clear cell renal cell carcinoma (ccRCC) are often diagnosed with both von Hippel-Lindau (VHL) mutations and the constitutive activation of hypoxia-inducible factor-dependent signaling. In this study, we investigated the effects of long-term hypoxia in 786-O, a VHL-defective renal cell...

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Publicat a:Int J Mol Sci
Autors principals: Chen, Szu-Chia, Chen, Feng-Wei, Hsu, Ya-Ling, Kuo, Po-Lin
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5751259/
https://ncbi.nlm.nih.gov/pubmed/29215599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18122657
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