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Application of Pharmacokinetics Modelling to Predict Human Exposure of a Cationic Liposomal Subunit Antigen Vaccine System

The pharmacokinetics of a liposomal subunit antigen vaccine system composed of the cationic lipid dimethyldioctadecylammonium bromide (DDA) and the immunostimulatory agent trehalose 6,6-dibehenate (TDB) (8:1 molar ratio) combined with the Ag85B-ESAT-6 (H1) antigen were modelled using mouse in-vivo d...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Badhan, Raj K. S., Khadke, Swapnil, Perrie, Yvonne
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750663/
https://ncbi.nlm.nih.gov/pubmed/29215597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics9040057
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