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The Development of a Melt-Extruded Shellac Carrier for the Targeted Delivery of Probiotics to the Colon

Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved bioavailability. However, most commercial enteric or pH-responsive polymers are relativel...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Gately, Noel M., Kennedy, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750644/
https://ncbi.nlm.nih.gov/pubmed/28937621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics9040038
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