Pharmacokinetics, Biodistribution, and Radiation Dosimetry for (89)Zr-Trastuzumab in Patients with Esophagogastric Cancer

Trastuzumab with chemotherapy improves clinical outcomes in patients with human epidermal growth factor receptor 2 (HER2)–positive esophagogastric adenocarcinoma (EGA). Despite the therapeutic benefit, responses are rarely complete, and most patients develop progression. To our knowledge, this is th...

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Veröffentlicht in:J Nucl Med
Hauptverfasser: O'Donoghue, Joseph A., Lewis, Jason S., Pandit-Taskar, Neeta, Fleming, Stephen E., Schöder, Heiko, Larson, Steven M., Beylergil, Volkan, Ruan, Shutian, Lyashchenko, Serge K., Zanzonico, Pat B., Weber, Wolfgang A., Carrasquillo, Jorge A., Janjigian, Yelena Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society of Nuclear Medicine 2018
Schlagworte:
Radiobiology/Dosimetry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750520/
https://ncbi.nlm.nih.gov/pubmed/28637800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.194555
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