Hepatocyte toll-like receptor 4 mediates lipopolysaccharide-induced hepcidin expression

Hepcidin expression is induced by inflammatory molecules such as lipopolysaccharide (LPS) via a macrophage-mediated pathway. Although hepatocytes directly respond to LPS, the molecular mechanism underlying toll-like receptor (TLR)-dependent hepcidin expression by hepatocytes is mostly unknown. Here...

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Pubblicato in:Exp Mol Med
Autori principali: Lee, Yong-Soo, Kim, Yong-Hoon, Jung, Yoon Seok, Kim, Ki-Sun, Kim, Don-Kyu, Na, Soon-Young, Lee, Ji-Min, Lee, Chul-Ho, Choi, Hueng-Sik
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750473/
https://ncbi.nlm.nih.gov/pubmed/29217822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.207
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