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Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments

Lassa virus (LASV) is an arenavirus whose entry into host cells is mediated by a glycoprotein complex (GPC) comprised of a receptor binding subunit, GP1, a fusogenic transmembrane subunit, GP2, and a stable signal peptide. After receptor-mediated internalization, arenaviruses converge in the endocyt...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Hulseberg, Christine E., Fénéant, Lucie, Szymańska, Katarzyna M., White, Judith M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750398/
https://ncbi.nlm.nih.gov/pubmed/29295909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01818-17
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