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Sensitive and Quantitative Detection of Anti-PEG Antibodies by mPEG-coated SPR Sensors

Pre-existing and induced anti-poly(ethylene glycol) (PEG) antibodies (abs) have been shown to be related with limitation of therapeutic efficacy and reduction in tolerance of several therapeutic agents. However, the current methods to detect anti-PEG abs are tedious and usually lack of quantificatio...

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Detalles Bibliográficos
Publicado en:Anal Chem
Main Authors: Zhang, Peng, Sun, Fang, Hung, Hsiang-Chieh, Jain, Priyesh, Leger, Kasey Joanne, Jiang, Shaoyi
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750323/
https://ncbi.nlm.nih.gov/pubmed/28727918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.7b02447
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