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RAD54 N-terminal domain is a DNA sensor that couples ATP hydrolysis with branch migration of Holliday junctions

In eukaryotes, RAD54 catalyzes branch migration (BM) of Holliday junctions, a basic process during DNA repair, replication, and recombination. RAD54 also stimulates RAD51 recombinase and has other activities. Here, we investigate the structural determinants for different RAD54 activities. We find th...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Goyal, Nadish, Rossi, Matthew J., Mazina, Olga M., Chi, Yong, Moritz, Robert L., Clurman, Bruce E., Mazin, Alexander V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750232/
https://ncbi.nlm.nih.gov/pubmed/29295984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02497-x
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