TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis

Although anti-tumor necrosis factor (TNF) agents are highly effective in the treatment of psoriasis, 2–5% of treated patients develop psoriasis-like skin lesions called paradoxical psoriasis. The pathogenesis of this side effect and its distinction from classical psoriasis remain unknown. Here we sh...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Conrad, Curdin, Di Domizio, Jeremy, Mylonas, Alessio, Belkhodja, Cyrine, Demaria, Olivier, Navarini, Alexander A., Lapointe, Anne-Karine, French, Lars E., Vernez, Maxime, Gilliet, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750213/
https://ncbi.nlm.nih.gov/pubmed/29295985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02466-4
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