The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types

Viroporins are small transmembrane proteins with ion channel activities modulating properties of intracellular membranes that have diverse proviral functions. Hepatitis C virus (HCV) encodes a viroporin, p7, acting during assembly, envelopment and secretion of viral particles (VP). HCV p7 is release...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Denolly, Solène, Mialon, Chloé, Bourlet, Thomas, Amirache, Fouzia, Penin, François, Lindenbach, Brett, Boson, Bertrand, Cosset, François-Loïc
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749900/
https://ncbi.nlm.nih.gov/pubmed/29253880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006774
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