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Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression

Cancer results from alterations at essential genomic sites and is characterized by uncontrolled cell proliferation, invasion and metastasis. Identification of driver genes of metastatic progression is essential, as metastases, not primary tumors, are fatal. To gain insight into the mutational concor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Krøigård, Anne Bruun, Larsen, Martin Jakob, Lænkholm, Anne-Vibeke, Knoop, Ann S., Jensen, Jeanette Dupont, Bak, Martin, Mollenhauer, Jan, Thomassen, Mads, Kruse, Torben A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749725/
https://ncbi.nlm.nih.gov/pubmed/29293529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189887
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