Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice

Presence of tubulointerstitial fibrosis is predictive of progressive decline in kidney function, independent of its underlying cause. Injury to the renal microvasculature is a major factor in the progression of fibrosis and identification of factors that regulate endothelium in fibrosis is desirable...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Loganathan, Krishnapriya, Salem Said, Ebtisam, Winterrowd, Emily, Orebrand, Martina, He, Liqun, Vanlandewijck, Michael, Betsholtz, Christer, Quaggin, Susan E., Jeansson, Marie
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749705/
https://ncbi.nlm.nih.gov/pubmed/29293543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189433
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