Enhancement of antibody-dependent cellular cytotoxicity of cetuximab by a chimeric protein encompassing interleukin-15

Enhancement of antibody-dependent cellular cytotoxicity (ADCC) may potentiate the antitumor efficacy of tumor-targeted monoclonal antibodies. Increasing the numbers and antitumor activity of NK cells is a promising strategy to maximize the ADCC of standard-of-care tumor-targeted antibodies. For this...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Ochoa, Maria Carmen, Minute, Luna, López, Ascensión, Pérez-Ruiz, Elisabeth, Gomar, Celia, Vasquez, Marcos, Inoges, Susana, Etxeberria, Iñaki, Rodriguez, Inmaculada, Garasa, Saray, Mayer, Jan-Peter Andreas, Wirtz, Peter, Melero, Ignacio, Berraondo, Pedro
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749662/
https://ncbi.nlm.nih.gov/pubmed/29308327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1393597
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