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Antitumor effect of a new nano-vector with miRNA-135a on malignant glioma

INTRODUCTION: MiR-135a is found to selectively induce apoptosis in glioma cell but not in normal neurons and glial cells. However, low transfection efficacy limits its application in vivo as other miRNAs. We prepared a new kind of nano-vector based on polyethylene glycol methyl ether (mPEG) and hype...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Liang, Chaofeng, Sun, Weitong, He, Haiyong, Zhang, Baoyu, Ling, Cong, Wang, Bocheng, Huang, Tengchao, Hou, Bo, Guo, Ying
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749566/
https://ncbi.nlm.nih.gov/pubmed/29343959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S148142
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